Specific Synchrotron Radiation Facilities Users Community (SpRUC)

Study group for structural analysis of skin stratum corneum and hair for the development of cosmetics and pharmaceuticals
Research Area Life Science, Measurements
Beamline              
SPring-8 BL40B2、BL40XU
NanoTerasuBL08W
Contact Hiromitsu Nakazawa
Affiliation:Teikyo University of Science
Email: h-nakazawa (at) ntu.ac.jp
Overview of Research Group, Goals and Purposes

The primary focus of this research group is the analyze interactions between formulation components and biological tissues, such as the skin stratum corneum and hair, which are important in the formulation design of transdermal/topical formulation and cosmetics. The aim is to revitalize synchrotron radiation research in this field by collaborating with researchers across related disciplines, widely sharing information, and promoting the global evolution and development of this research area.
Synchrotron radiation is essential for structural analysis of biological samples with low crystallinity, such as the stratum corneum, as well as for elucidating subtle structural changes that occur on the skin surface following the penetration of substances, including solutions. Such research would be extremely difficult to conduct without synchrotron-based techniques. Therefore, within this research committee, researchers from industry, government, and academia will collaborate to gather a wide range of requests for synchrotron radiation experiments that may serve as a foundation for research on skin-applied preparations, while also promoting the development of new users and ensuring stable access to experimental opportunities.
In addition, the group will engage in broad discussions on the current state of the research field, its technical problems, future expansion potential, and the development of new measurement methodologies. Based on these discussions, recommendations will be compiled and provided to synchrotron radiation facilities such as SPring-8. Through these efforts, the group aims to contribute to the future advancement of synchrotron radiation research.