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X-ray diffraction microscopy

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X-ray diffraction microscopy is a unique technique to reconstruct a sample image from its oversampled diffraction intensity pattern. Using this technique, one can determine electron density distribution without need of sample crystallization.
The following figures show the diffraction intensity pattern and the 2D reconstruction of Escherichia coli bacteria.

Fig. X-ray diffraction intensity pattern of Escherichia coli bacteria

Fig. Image of Escherichia coli bacteria reconstructed from the diffraction intensity pattern

[ J. Miao, K. O. Hodgson, T. Ishikawa, C. A. Larabell, M. A. LeGros and Y. Nishino, Proceedings of National Academy of Science of the USA 100, 110-112 (2003), Fig. 1A, 2,
©2003 National Academy of Science ]

 

Scientific keywords

A. Sample category inorganic material, organic material, biology, medicine
B. Sample category (detail) metal, alloy, semiconductor, insulator, ceramics, solid-state crystal, amorphous, glass, organism, cell, biological material
C. Technique X-ray diffraction
D. Technique (detail) coherent scattering, phase measurement, speckle
E. Particular condition 2D imaging, 3D imaging (cf. CT), X-ray microscopy
F. Photon energy X-ray (4-40 keV)
G. Target information structure analysis

Industrial keywords

level 1---Application area Pharmaceuticals
level 2---Target drug design, food, Environmental material
level 3---Target (detail) organism
level 4---Obtainable information
level 5---Technique diffraction, imaging

Inquiry number

SOL-0000000970

Last modified 2019-11-21 16:52
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