SPring-8, the large synchrotron radiation facility

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DEI イメージング

  • Only SPring-8
  • For beginners

Inquiry number

SOL-0000001445

Beamline

BL20B2 (Medical and Imaging I)

Scientific keywords

A. Sample category biology, medicine, research on method, instrumentation
B. Sample category (detail) organic material, macromolecule, biology (in vivo), biology (in vitro), organism, cell, biological material, biomolecule, crystal, biomolecule, noncrystal
C. Technique X-ray diffraction, absorption and its secondary process
D. Technique (detail) reflection, refraction
E. Particular condition 2D imaging, interface, room temperature
F. Photon energy X-ray (4-40 keV), X-ray (> 40 keV)
G. Target information morphology

Industrial keywords

level 1---Application area Pharmaceuticals
level 2---Target process analytical technology (PAT)
level 3---Target (detail) drug
level 4---Obtainable information density, crack, crevice, molphology
level 5---Technique imaging

Classification

A80.50 Pharmaceuticals

Body text

DEI (Diffraction Enhanced Imaging)は,屈折率の違いに基づいて物体のX線画像を造るユニークな方法です。分解能0.2ミリから20ミクロン程度までの観察に向いています。下の画像はアクリルの円柱の画像で,他の方法では得られないコントラストが得られています。

 

[ K. M. Pavlov, T. E. Gureyev, D. Paganin, Y. I. Nesterets, M. J. kitchen, K. K. W. Siu, J. E. Gillam, K. Uesugi, N. Yagi, M. J. Morgan and R. A. Lewis, Nuclear Instruments and Methods in Physics Research A 548, 163-168 (2005), Fig. 2,
©2005 Elsevier Science Publisher ]

Source of the figure

Original paper/Journal article

Journal title

Nuclear Instruments and Methods in Physics Research A 548 (2005) 163–168

Figure No.

2

Technique

Source of the figure

No figure

Required time for experimental setup

1 shift(s)

Instruments

References

Document name
Nuclear Instruments and Methods in Physics Research A 548 (2005) 163–168

Related experimental techniques

Questionnaire

The measurement was possible only in SPring-8. Impossible or very difficult in other facilities.
This solution is an application of a main instrument of the beamline.

Ease of measurement

Easy

Ease of analysis

Easy

How many shifts were needed for taking whole data in the figure?

Less than one shift

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